Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE−/− Mice
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چکیده
منابع مشابه
Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE−/− Mice
AIMS To investigate whether ginkgolide B (a platelet-activating factor inhibitor) affects vascular inflammation in atherosclerosis-prone apolipoprotein E-deficient (ApoE(-/-)) mice. METHODS AND RESULTS Human platelets were used to evaluate the effects of ginkgolide B on platelet aggregation and signal transduction. Ginkgolide B attenuated platelet aggregation and inhibited phosphatidylinosito...
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Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115; Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 430022, and; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Division, Vanderbilt Unive...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0036237